I am usually late to the party on a lot of the cutting edge things in WordPress. One thing I have used as a default for years is Akismet for managing spam comments on installations. It works very well but can be a hassle to setup and costs money if you are doing anything serious or businessy. Eventually I just ended up ignoring comments as the box just fills with spam comments.
Seeing this I thought: “Brain, why dont we just put a list of common spam terms into this list and be done with at least 60% of the spam we get in comments?” and I thought back: “That sounds great but I bet someone smarter already thought of this so lets check the Googles!”
Pleasantly after searching for “good words for wordpress comment blacklist” I clicked the first result: https://gist.github.com/splorp/1385930 which links to the useful result here: https://github.com/splorp/wordpress-comment-blacklist.
It sounds like enough people have checked this thing against Akismet and it cuts mustard. Happy hunting.